Page 39 - 2018食藥署年報(英文版)

Unknown Powder Chlorantraniliprole

Figure2-19 Comparison of the structure of unknown powder (new pesticide) and chlorantraniliprole

rare pesticides named Nitenpyram and Chlorantraniliprole derivatives were identified.
Nitenpyram is an animal acaricide and is banned for use on animals destined for human

consumption. The chemical structure of nitenpyram is very similar to Fipronil and is not allowed
to be used in food. The derivative of chlorantraniliprole is first discovered and reported in the
literature. Its chemical name (IUPAC) is 3-bromo-1-(3-chloro-2-pyridinyl)-N-[2,4-dichloro-6-
(isopropyl carbamoyl)phenyl. ]-1H-pyrazole-5-carboxamide, and is a newly synthesized pesticide
(Figure 2-19). Because the compounds could not be detected by any routine inspection, it is
fortunate that these illegal materials were blocked at the border and not delivered to the market.

(2) The development and application of high throughput screening technique
TFDA employed the newest international trend high-resolution mass spectrometer with
a non-target analysis mode, and applied high-throughput technique for screening the unknown
hazardous substances in foods through the database comparison. The database covered more than
3000 compounds of preservatives, antioxidants, and other additives and chemicals. The self-
established 47 colorants database was constructed with the retention time, the exact molecular

weight of precursor ion, and two pairs of product ions. TFDA keeps on updating and increasing
the item of colorants in the database. A survey of 80 commercial beverages and candy showed that
3 samples were not complied with labeling regulation. On the other hand, for the other 79 sample
(62 cases form the border and 17 cases form the local inspection centers), 17 samples were found
with illegal colorants, and 2 were found with unlabeled legal colorants.

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