Cheng-Han Chung ^a, Szu-Chien Yeh ^b, Huang-Chung Tseng ^c, Ma-Li Siu ^b,
Kung-Ta Lee ^a,*

^a Department of Biochemical Science and Technology, National Taiwan University, Taipei 10617, Taiwan
^b Natural Resource Development Institute of Pharmaceutics, Development Center for Biotechnology, New Taipei City 22180, Taiwan
^c Joben Bio-medical Company, Pingtung County 908, Taiwan

 

The fruiting body of Antrodia cinnamomea is used as a medicinal mushroom in Taiwan and is found on the inner cavity of the endemic species Cinnamomum kanehirai. In this study, phytomics similarity index (PSI) analysis was employed for the chemical quality evaluation of the A. cinnamomea fruiting bodies from different strains, and grown on various substrates. The results indicated that the different types of A. cinnamomea fruiting bodies contain eight index compounds, and that it was difficult to discriminate between them solely on the basis of those index compounds. In our research, we used PSI scores to assess the metabolite similarity of the fruiting bodies of A. cinnamomea. It was revealed that fruiting bodies from various A. cinnamomea strains grown on different culture substrates produce distinct PSI scores. We concluded that PSI analysis had good selectivity on the different types of A. cinnamomea fruiting bodies.

 

Keywords: Antrodia cinnamomea, metabolite profiles, phytomics similarity analysis