Evaluation of the ID Number Method for Structure Generation and Complete Assignment of NMR Spectra of Erythromycin A

SHENG-CHIH CHEN* AND JIN-CHERNG LIEN

Graduate Institute of Pharmaceutical Chemistry, China Medical University, 91 Hsueh-Shih Rd., Taichung City 404, Taiwan, R.O.C.

(Received: April 8, 2004; Accepted: September 13, 2004)

ABSTRACT

   The present paper describes the evaluation of the ID number method for the structure generation and complete assignments of proton and carbon NMR spectra of erythromycin A. This study revised the errors found in previous assignments of two carbon signals in the spectra of this compound.

Key words: erythromycin A, structure generation, ID number method, NMR spectra