Journal of Food and Drug Analysis (JFDA)
【Update Date:2010-08-26】unit:
Occurrence of Tetrodotoxin Poisoning in Nassarius Papillosus Alectrion and Nassarius Gruneri NiothaFANG-MING LIU, YOU-MING FU AND DANIEL YANG-CHIH SHIH*
Bureau of Food and Drug Analysis, Department of Health, Executive Yuan, 161-2 Kunyang St., Nangang District, Taipei City 115, Taiwan, R.O.C.(Received: July 28, 2003; Accepted: March 31, 2004)ABSTRACT
On May 15, 2002, a food poisoning case caused by consumption of unknown gastropods was reported. Symptoms included vomiting, diarrhea and other neurological symptoms developed 2 hr after ingestion of gastropods. The unknown species of gastropod were later identified to be Nassarius Papillosus Alectrion and Nassarius Gruneri Niotha. Using a tetrodotoxin bioassay, the two samples showed toxicity of 320 and 386 mouse units per gram (MU/g) in Nassarius Papillosus and Nassarius Gruneri. The result of high performance liquid chromatography (HPLC) on the purified toxin indicated that the causative toxic agents were tetrodotoxin and its derivative anhydrotetrodotoxin.Key words: gastropod, Nassarius Papillosus Alectrion, Nassarius Gruneri Niotha, tetrodotoxin, anhydrotetrodotoxin