Precision nanomedicine for anxiety: Challenges, opportunities, and future directions in targeted drug delivery

Sehrabpreet Singh*, Amanpreet Singh, Shruti, Shailesh Sharma

Department of Pharmaceutics, Amar Shaheed Baba Ajit Singh Jujhar Singh Memorial College of Pharmacy, Bela, Ropar, Punjab, 140111, India

Nanoparticle-based drug delivery system represents one of the challenging strategies suggested to improve anxiety disorder therapeutic approaches, clinic challenges of delayed action, side effect-free designing and poor patient compliance. Traditional pharmacological agents can increase drug bioavailability and target specific brain regions, whereas nanoparticle-mediated controlled release offers enhanced precision and sustained action. The others in this review concentrate on several kinds of nanoparticle, including lipid-based, polymeric-metallic, and responsive nano-particles, their use in anxiety medication. In addition, emphasis is placed on precision medicine that pertain the delivery of treatment based on an individual's genetic, environmental and lifestyle aspects. Also, it is looked into how artificial intelligence is being integrated into personalized nanoparticle formulations. Toxicity, regulatory hurdles and scalabilityare briefly discussed and future directions on smart and biodegradable nanoparticles are underlined. The present review highlights advantages of nanoparticle treatments and outlines a future direction of precision nanomedicine for anxiety.