Detection of Abused Drugs in Urine by GC-MS

MEI-CHICH HSU^1*, DAPHNE CHEN² AND RAY H. LIU³

1. Graduate Institute of Sports Science, National Sport University, Taoyuan County, Taiwan (ROC)
2. Biology Department, University of California, San Diego, California, USA.
3. Department of Medical Technology, Fooyin University, Kaohsiung County, Taiwan, R.O.C.

(Received: January 7, 2009 ; Accepted: July 29, 2009)

ABSTRACT

   This paper reviews gas chromatography-mass spectrometry (GC-MS) methods for the analysis of amphetamines, ketamines, opioids, cocaine, and other abused drugs in urine that were developed by authors in Taiwanese institutions, and published during the 2000 to early 2008 period. Information on sample preparation, derivatization, internal standard, GC column, detection mode, and validation data for the reported methods are summarized in table format to facilitate readers’ reference and adaptation.

Key words:Review, GC-MS, amphetamines, ketamine, cocaine, opioids