Evaluation of Five Commercial Amphetamines and Opiates Immunoassay Test Kits in Taiwan

SHYI-MIIN HWANG, SU-HWA HUANG, BIN-CHUNG HUANG AND CHUN-SHENG CHIEN

National Laboratories of Foods and Drugs,Department of Health, Executive Yuan

ABSTRACT

   Five commonly used commercial amphetamines (AMs) and opiates (OPs) immunoassay test kits: HYCOR accuPINCHTM, Drug Screening System (DSS) MACH TVR ScreenTM, Princeton BioMeditech (PBM) BiosignTM and International Diagnostic Systems I.D. BlockTM were evaluated for their cutoff verification and assay performance with standardized and confirmed urine specimens. Cutoff verification was evaluated at several cutoffs for commercial AMs and OPs test kits. The assay performance was evaluated with authentic urine specimens confirmed by GC/MS. Results indicated that the real cutoffs for most AMs or OPs test kits were lower than those reported. accuPINCHTM, AbuSignTM and I.D.BlockTM were better than MACH IVR ScreenTM and ONTRAKTM for AMs test kits; accuPINCHTM, AbuSignTM, I.D.BlockTM and ONTRAKTM were better than MACH IVR ScreenTM for OPs test kits.

Key words :Methamphetamine, Morphine, Immunoassay, Test kits