Applications of Capillary Electrophoresis in Pharmaceutical Drug Analysis

Cheng-Ming Liu* and Yew-Min Tzeng

Institute of Biotechnology, National Dong Hwa University, Shoufeng, Hualien, Taiwan, R.O.C.

 ABSTRACT

   Capillary electrophoresis (CE) is a new analytical technique that has been applied to many fields including biomedical technology, clinical diagnosis, pharmaceutical drug analysis, food science, and environmental analysis. This article reviews the use of CE in the analysis of drugs, with the drugs being categorized by their major mode of pharmacological action. From selected paper, methods are brief described. These descriptions include the mode of CE, the composition of the running buffer, detection methods, sample preparation and running conditions.

Key words: capillary electrophoresis, capillary zone electrophoresis, micellar electrokinetic chromatography, running conditions, drug analysis